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Inhaled nitric oxide in the first week of life helps the eyes of babies with PPHN
For very preterm babies, inhaled nitric oxide in the first week of life seems to help both persistent pulmonary hypertension of the newborn (PPHN) and retinopathy. After the first week, though, inhaled nitric oxide wasn't associated with better outcomes. Inhaled nitric oxide could be reframed as multi-organ protection for very premature babies with PPHN. Read the Nature article
Robyn Kalda
Oct 271 min read
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Economic analysis of virtual vs. centre-based pulmonary rehabilitation
This study compared the costs of an 8-week centre-based pulmonary rehabilitation program to a virtual program. Costs and outcomes were...
Robyn Kalda
Oct 141 min read
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Pericardial effusion in patients treated with sotatercept
Because a drug trial for another drug similar to sotatercept was stopped when it was found to be associated with pericardial effusion...
Robyn Kalda
Oct 21 min read
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Distinct blood vessel lining in CTEPH
In chronic thromboembolic pulmonary hypertension (CTEPH), this study found that the cells lining blood vessels (the endothelium) are...
Robyn Kalda
Sep 151 min read
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Very premature babies with PH who respond to inhaled nitric oxide have better survival
A study looked at 262 very premature babies diagnosed with pulmonary hypertension who were given inhaled nitric oxide. For babies whose...
Robyn Kalda
Sep 11 min read
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New PAH-associated genes identified
In the body, variations in several genes were associated with a more than 20-fold increased risk of pulmonary arterial hypertension...
Robyn Kalda
Aug 291 min read
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Uric acid might cause PAH
Other studies have shown a relationship between high levels of uric acid and pulmonary arterial hypertension (PAH). This study looked at...
Robyn Kalda
Aug 181 min read
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Non-oral therapies burden PAH patients
This study looked at the challenges and impacts of non-oral treatments for pulmonary arterial hypertension (PAH), beyond those caused by...
Robyn Kalda
Aug 41 min read
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Early dual treatment helps late-diagnosed PAH patients catch up
Early use of dual therapy helps newly-diagnosed pulmonary arterial hypertension patients do as well as patients six months past...
Robyn Kalda
Jul 211 min read
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Good news: treatments have significantly increased five-year survival for CTEPH
Since the 1980s, treatment options for patients with chronic thromboembolic pulmonary hypertension (CTEPH) have increased. This study...
Robyn Kalda
Jul 181 min read
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Hymecromone clinical trial is cautiously positive
A very small (16 patients) phase 2a clinical trial for pulmonary hypertension associated with interstitial lung disease (PH-ILD) looked...
Robyn Kalda
Jul 71 min read
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Meth-associated PAH care gaps: closing the divide
We know methamphetamine use is associated with pulmonary arterial hypertension (PAH), but this population's care needs haven't been...
Robyn Kalda
Jun 231 min read
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IV selexipag can be used as a bridging therapy
Pulmonary arterial hypertension patients who take selexipag normally take it orally (as a pill). Sometimes, though, this is temporarily...
PHA Canada
Jun 91 min read
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Prostacyclin analogues for CTEPH?
This systemic review summarized the data from six studies that examined whether prostacyclin analogues are safe and useful when used to...
PHA Canada
May 261 min read
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Some PAH patients on sotatercept can stop taking prostacyclin analogues
In a small study of 34 pulmonary arterial hypertension (PAH) patients taking triple therapy plus sotatercept, some were able to stop...
PHA Canada
May 121 min read
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Poverty and isolation are associated with worse pulmonary hypertension outcomes
A 2024 study looked at the association between socioeconomic disadvantage and pulmonary hypertension. In one New York hospital system,...
PHA Canada
Apr 281 min read
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Some PH patients with interstitial lung disease may benefit from oral PAH drugs
Medications for pulmonary arterial hypertension (PAH) are not approved for use in patients with pulmonary hypertension due to...
PHA Canada
Apr 141 min read
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ZENITH results published: sotatercept is effective for high-risk PAH patients
The ZENITH study examined whether adding sotatercept to people's ongoing therapies reduced the risk of death, lung transplantation, or...
PHA Canada
Apr 81 min read
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Main pulmonary artery diameter predicts risk in PAH patients
Researchers wanted to know whether an enlarged pulmonary artery could independently predict risk in pulmonary arterial hypertension (in...
PHA Canada
Mar 311 min read
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Plain-language summary available for the TORREY seralutinib study
Seralutinib is a molecule that blocks inflammation, cell proliferation, and scarring responsible for pulmonary arterial hypertension. The...
PHA Canada
Mar 171 min read
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