Prostacyclin analogues protect against age-related macular degeneration

Robyn Kalda
Nov 10, 2025
1 min read

A study found that people taking infused prostacyclin analogues for pulmonary hypertension had a significantly lower risk of developing age-related macular degeneration, an eye problem that causes vision loss in older adults. The protection was robust -- patients using systemic prostacyclin analogues were about 60% less likely to develop several types of age-related macular degeneration -- and the effect was sustained over time.

Read the Eye article

Recent Posts

Using sotatercept off-label in children

Clinical trials for sotatercept didn't include children, so any pediatric use is off-label. This study, conducted at one children's hospital in San Diego, evaluated sotatercept in 7 pediatric patients

Phase 1 trial of treprostinil prodrug patch succeeds

A 9-participant phase 1 clinical trial used a patch to deliver a prodrug of treprostinil (a prodrug is something that is metabolized into the drug in question inside the body). Each participant wore a

Sotatercept lowers blood volume but increases exercise ability

In a study of a relatively low-risk population of pulmonary hypertension patients, researchers began to untangle sotatercept's complex effects on exercise. Sotatercept lowered blood volume to normal l

Comments