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Using sotatercept off-label in children

Clinical trials for sotatercept didn't include children, so any pediatric use is off-label. This study, conducted at one children's hospital in San Diego, evaluated sotatercept in 7 pediatric patients with pulmonary arterial hypertension who were already on triple therapy. A majority of patients had favourable hemodynamics trends, supporting the need for official pediatric studies.


 
 
 

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3 Comments


Lillie Nicolas
Lillie Nicolas
3 days ago

While the sample size is small, it's valuable to see data being collected for children with pulmonary arterial hypertension, especially since treatment options are often based on adult studies. Hopefully, free top games these findings will lead to larger clinical trials and clearer guidance on the safety and effectiveness of sotatercept in pediatric patients.

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