Systematic review of treatment strategies to reach low-risk status in PH

6 days ago

1 min read

A systematic review examined the evidence linking individual pulmonary hypertension treatment strategies to low-risk status and long-term outcomes. 48 reports were included.

Few patients reached low-risk status. Prostacyclin pathway therapy and add-on sotatercept improved clinical outcomes. Low-risk status predicted survival, but people initially at low risk did not often stay low risk: the risk category at their first annual review predicted the later disease course. Studies disagreed on whether patients at low risk benefit from more treatment.

Read the Cureus review

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