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Prostacyclin analogues for CTEPH?

May 26, 2025
1 min read

This systemic review summarized the data from six studies that examined whether prostacyclin analogues are safe and useful when used to treat chronic thromboembolic pulmonary hypertension (CTEPH). They found similar safety results in the placebo and prostacyclin groups, and a trend toward improvement in several clinical measures, but they note the evidence remains "insufficient and controversial". More work is needed.


 
 
 

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8 Comments


james li
Aug 13

The systematic review of only six studies really highlights how scarce the evidence is for prostacyclin analogues in CTEPH, and that “insufficient and controversial” line is so telling. It’s good to see safety wasn’t a concern, but we clearly need more robust trials before drawing conclusions. By the way, I keep a home café brewing guide I like to share: https://homecafelab.com/

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