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Environmental triggers may contribute to heritable PAH

This study tried to identify new environmental triggers or genetic causes in heritable pulmonary arterial hypertension. They found several potential genes for further exploration, but they also found consistent toxin exposure on one of the families they were investigating. They conclude that environmental triggers should also be investigated in heritable PAH.


 
 
 

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Clinical trials for sotatercept didn't include children, so any pediatric use is off-label. This study, conducted at one children's hospital in San Diego, evaluated sotatercept in 7 pediatric patients

 
 
 

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