top of page

BET Protein Inhibition for Pulmonary Arterial Hypertension

Updated: Nov 7, 2024

This pilot study added apabetalone to people's PAH therapy twice daily for 16 weeks to see if a future clinical trial evaluating bromodomain inhibition in pulmonary arterial hypertension might be feasible. They also aimed to provide preliminary evidence that apabetalone may be safe and effective in PAH.



 
 
 

Recent Posts

Promising results for drug candidate CS1

This press release reports that over the 12 months of their Expanded Access Program enrolling ten patients, the majority of patients with pulmonary arterial hypertension who completed treatment with d

 
 
 
Using sotatercept off-label in children

Clinical trials for sotatercept didn't include children, so any pediatric use is off-label. This study, conducted at one children's hospital in San Diego, evaluated sotatercept in 7 pediatric patients

 
 
 

Comments


PHA Canada

408 - 55 Water Street

Office 8928

Vancouver, BC, V6B 1A1

Email: info@phacanada.ca

Phone: 604-682-1036

Toll Free: 1-877-774-2226

Charitable Registration # 872050224RR0001

  • Instagram
  • Facebook
  • X
  • LinkedIn
  • Youtube

Copyright 2025 PHA CANADA, ALL RIGHTS RESERVED   |   Website created by Creativibe

bottom of page