Many health awareness campaigns around the world attribute the progression of diseases to environmental and lifestyle factors; however, genetics is often forgotten. For many diseases, a patient’s genetics is an important biological driver. Genetics is a branch of biology focusing on genes, heredity and genetic variation. All of these combine to explain how traits and diseases can be passed from parents to their children through DNA. In a consensus report summarizing the 7th World Symposium...

In 2023, the Pulmonary Vascular Research Institute (PVRI) launched a Pulmonary Hypertension Global Patient Survey. The first global survey of those living with pulmonary hypertension (PH) and their caregivers, it aimed to help clinicians better understand the impacts of pulmonary hypertension on patients. Pulmonary hypertension affects people of all ages, genders and demographics, so a truly global response is required. As the only global pulmonary vascular disease charity, the PVRI is...

PHocus study succeeds The PHocus study, a Phase 2 trial evaluating the safety and effectiveness of the new drug mosliciguat for pulmonary hypertension associated with interstitial lung disease. (PH-ILD), reported good results. After 16 weeks of taking mosliciguat, participants’ pulmonary vascular resistance dropped by over half, their six-minute walk distance increased by 35m, and their NTproBNP level also dropped by half. Based on these very encouraging results, Pulmovant began a larger...