Study Shows Benefits of Pulmonary Angioplasty for Pulmonary Hypertension

11.21.2012

Source: TCTMD

Percutaneous Transluminal Pulmonary Angioplasty for the Treatment of Chronic Thromboembolic
Pulmonary Hypertension

By Yael Maxwell
Thursday, November 15, 2012

Pulmonary artery angioplasty improves subjective symptoms and hemodynamics at a tolerable level in patients with chronic thromboembolic pulmonary hypertension, according to a small study published online November 6, 2012, ahead of print in Circulation: Cardiovascular Interventions. While the procedure does not produce any immediate hemodynamic improvement, a measurable therapeutic effect is seen after several months.

Toru Satoh, MD, of Kyorin University School of Medicine (Tokyo, Japan), and colleagues looked at 29 patients with chronic thromboembolic pulmonary hypertension who underwent angioplasty ....

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29 patients underwent 51 procedures, January 2009 to December 2011.

One patient died 2 days after PTPA, and pulmonary edema occurred with 27 procedures (53%)

  • No immediate hemodynamic effects seen, but NYHA functional class and mean plasma BNP levels improved at 6 months (P <0.01 for both)
  • By 6 months, pulmonary pressure decreased from 45.3 mm Hg to 31.8 mm Hg, and cardiac output rose from 3.6 L/min to 4.6 L/min (P < 0.01 for both)

Implications: Pulmonary artery angioplasty may prove to be a therapeutic option in patients with chronic thromboembolic pulmonary hypertension.

Kataoka M, et al. Circ Cardiovasc Interv.
2012;Epub ahead of print.

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