Special Stem Cells May Participate in Pulmonary Hypertension Lung Repair, Study Reports
A small group of stem cells may help repair the lungs of those with pulmonary hypertension (PH), chronic obstructive pulmonary disease (COPD), and other lung conditions, according to a study.
Actelion obtains “Epoprostenol Act” label extension for pediatric PAH patients in Japan
Actelion (SIX: ATLN) announced today that Japan's Ministry of Health, Labor and Welfare granted a label extension for dosage and administration for "Epoprostenol ACT" (0.5 mg and 1.5 mg) for the treatment of pediatric patients with pulmonary arterial hypertension (PAH).
Pulmonary Arterial Hypertension and Genetics: Interview With the Experts
In recent years, treatment advances have improved the survival rates of individuals with pulmonary arterial hypertension (PAH), a rare but devastating disease that affects an estimated 10 to 52 people per million.1,2 In addition, developments in genetics and genomics technology have begun to illuminate the mechanisms underlying the pathogenesis of PAH.
Evidence review supports pediatric use of PDE 5 inhibitors for pulmonary hypertension
A systematic review of the comparative effectiveness and safety of phosphodiesterase type 5 (PDE-5) inhibitors in pediatric patients with pulmonary hypertension published Feb. 24, 2017 in Pediatrics demonstrates that scientific evidence supports the use of this class of medications in infants, neonates and children with pulmonary hypertension. In this review, these medicines were shown to improve echocardiography measurements, cardiac catheteriza…
Statins May Boost Survival Chances Among Advanced Pulmonary Hypertension Patients, Study Finds
Pulmonary hypertension (PH) patients who take statins live longer than those who don’t — despite similar histories of hospitalization in both groups.
IV-delivered Stem Cells Show Potential as Pulmonary Hypertension Therapy, Rat Study Shows
IV delivery of stem cells to rats with pulmonary arterial hypertension (PAH) reduced the animals’ harmful lung blood vessel remodeling and improved their blood flow, a study reports. Researchers said the implication was that the stem cells could be used as a treatment for PAH. They used a type of stem cell known as an mesenchymal stromal cell, or MSC, in their study.
Blocking Factor in Lungs Could Be Way to Treat Clotting Form of Pulmonary Hypertension
The discovery of a molecular factor that triggers blood clots in lung arteries may explain why chronic thromboembolic pulmonary hypertension (CTEPH) often occurs in patients without traditional clotting risk factors, according to a study.
SERAPHIN Trial: Study Finds Macitentan Can Improve Quality of Life for Some PH Patients
Patients with WHO Group 1 PH (PAH, pulmonary arterial hypertension), a serious, progressive and often fatal lung disease, typically have a number of symptoms and limitations that affect the quality of everyday living. Depending on the severity of the disease, patients may experience negative physical, social, emotional and psychological impacts. Research has indicated that >macitentan (Opsumit®), an endothelin receptor antagonist (ERA), might hel…
First Canadian Electrophysiology Laboratory Equipped with Robotic Magnetic Navigation System Dedicated to Patients with Congenital Heart Diseases
The Montreal Heart Institute is proud to announce the opening of the very first electrophysiology laboratory (EP Lab) equipped with robotic and magnetic navigation and dedicated to congenital heart diseases in Canada. Congenital heart diseases are cardiac malformations that affect approximately 1% of all Canadians. “The eimplementation of this cutting edge technology is a major advance. Thanks to this new lab, we will be able to perform intervent…
Merryman wins $6M to address heart disease with arthritis drug, fund other research
A Vanderbilt biomedical engineering professor has garnered $6 million total in grants to determine how to treat heart valve disease, pulmonary hypertension and heart failure using drugs originally developed for rheumatoid arthritis and applying the lessons learned from failed weight loss drugs.
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