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Galectin-3 strong prognostic marker in patients with pulmonary hypertension
ORLANDO, Fla. — Patients with pulmonary hypertension and elevated galectin-3 were more likely to have a higher mortality rate at 4 years compared with patients with lower levels of the biomarker, according to data presented at the Annual Scientific Meeting of the Heart Failure Society of America. Previous research has linked high levels of galectin-3 to increased mortality in HF. However, the association had not been studied in patients with p…
Bayer receives approval for Adempas® as first drug to treat rare heart and lung disease
Adempas® (riociguat) offers new hope for patients suffering from chronic thromboembolic pulmonary hypertension (CTEPH) Adempas® is now available in Canada as the first and only drug indicated to manage the treatment of chronic thromboembolic pulmonary hypertension (CTEPH)1,2 TORONTO, Sept. 23, 2013 /CNW/ - Bayer Inc. announced today the Health Canada approval of Adempas® (riociguat). Adempas® is the first drug indicated to manage the treatment …
Actelion Pharmaceuticals Canada Introduces CARIPUL® (epoprostenol) For Injection, A Treatment for Pulmonary Arterial Hypertension
Actelion Pharmaceuticals Canada Inc. announced today that CARIPUL® (epoprostenol) for Injection is now available in Canada. CARIPUL® is a prescription medication indicated for the long-term intravenous treatment of primary pulmonary hypertension (or idiopathic pulmonary arterial hypertension), and secondary pulmonary hypertension due to scleroderma spectrum of diseases in NYHA functional Class III and Class IV patients who did not respond ade…
Cuba grad awaiting double lung transplant
Imagine not being able to laugh or cry without feeling as if you were suffocating. Imagine going from an active lifestyle to not being able to walk even a short distance without losing your breath. Imagine being on oxygen 24 hours a day. Imagine your heart being six times larger than average and covering three-fourths of a lung. Imagine if the only chance you had to live was to have a double lung transplant that costs nearly $800,000. And no…
A categorically novel finding: Fighting against severe and progressive pulmonary hypertension
Pulmonary hypertension (PH) is a condition characterized by increased blood pressure in the lungs. It frequently leads to early death in patients. Numerous macrophages, which are cells that mainly engulf and digest cellular debris and pathogens, are found around the lung vessels of patients with PH. These perivascular macrophages express high levels of the enzyme required for the production of leukotriene B4 (LTB4), which induces inflammation and…
New England Journal of Medicine Publishes Macitentan Morbidity and Mortality Study in PH
Canada NewsWire LAVAL, QC, Aug. 29, 2013 Macitentan significantly reduced risk of morbidity/mortality events Macitentan currently in world-wide regulatory review LAVAL, QC, Aug. 29, 2013 /CNW/ - Actelion Pharmaceuticals Canada Inc. announced today that the New England Journal of Medicine (NEJM) has published the results of SERAPHIN (Study with Endothelin Receptor Antagonist in Pulmonary Arterial Hypertension to Improve Clinical Outcome), …
EU Panel Backs Bayer's Riociguat for Pulmonary Hypertension
Canada NewsWire LAVAL, QC, Aug. 29, 2013 Macitentan significantly reduced risk of morbidity/mortality events Macitentan currently in world-wide regulatory review LAVAL, QC, Aug. 29, 2013 /CNW/ - Actelion Pharmaceuticals Canada Inc. announced today that the New England Journal of Medicine (NEJM) has published the results of SERAPHIN (Study with Endothelin Receptor Antagonist in Pulmonary Arterial Hypertension to Improve Clinical Outcome), …
Blocking molecular pathway reverses pulmonary hypertension in rats
Pulmonary hypertension, a deadly form of high blood pressure that develops in the lungs, may be caused by an inflammation-producing molecular pathway that damages the inner lining of blood vessels, according to a new study by researchers at the Stanford University School of Medicine. The results, which will be published Aug. 28 in Science Translational Medicine, suggest that using medications to block this pathway could lead to the first-known…
Teen survives double-lung transplant, but is upset about missing One Direction concert
BRAMPTON— Every breath Amanda Kakoz, 13, takes, she sort of owes it to an organ donor. Last month, the Brampton teen, underwent a double-lung transplant after battling pneumonia. Amanda has pulmonary hypertension, a type of high blood pressure affecting the arteries in the lungs and the right side of her heart. When Amanda was a baby, her parents were warned that if medication failed, lung transplantation was the only cure. Amanda enjoye…
COMP student inspires, educates while battling pulmonary hypertension
When Sean Wyman was diagnosed with pulmonary hypertension (PH) at 18, doctors told him the severity of the illness would prevent him from ever working or going to school. But Wyman was destined for more than that. He graduated from UC Riverside in 2011 with a bachelor’s in psychology, earned a Master of Science in Medical Sciences from Western University of Health Sciences the following year, and enrolled in WesternU’s College of Osteopathic …
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